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Impacts of cigarette smoking on immune responsiveness: Up and down or upside down? PMC Smoking: Progressive Lung Damage and Respiratory Decline Smoking causes cumulative structural and functional damage to the respiratory system through chronic exposure to toxic chemicals and particulate matter. Inhaled toxins impair ciliary function How cigarette smoke skews immune responses to promote infection, lung disease and cancer Nature Reviews Immunology Smoking cessation and vascular endothelial function Hypertension Research The Impact Of Smoking On Arthritis The Arthritis Movement Health Effects of Smoking on Your Body

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